Intralesional Rituximab in the Treatment of Refractory Oral Pemphigus Vulgaris
نویسندگان
چکیده
منابع مشابه
Intralesional Rituximab in the Treatment of Refractory Oral Pemphigus Vulgaris.
IMPORTANCE Oral lesions of pemphigus vulgaris are usually recalcitrant and respond slowly to treatments. Corticosteroid injection is considered to be the most effective local treatment in oral pemphigus vulgaris. However, intralesional corticosteroids are not effective in all remnant lesions. In 3 such patients with pemphigus vulgaris, we evaluated the utility of 2 injections (on days 1 and 15)...
متن کاملRituximab in the Treatment of Pemphigus Vulgaris
INTRODUCTION Rituximab is increasingly used in patients with pemphigus vulgaris (PV) who are nonresponders to conventional therapy. METHODS A PubMed search was conducted using the words pemphigus vulgaris and rituximab therapy from papers published between 2000 and 2012. Two protocols were used. In the lymphoma protocol, patients received four weekly infusions of rituximab (dose 375 mg/m(2))....
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Background: Recently, rituximab has been successfully used for the treatment of pemphigus family, the main subtype of which is pemphigus vulgaris (PV). The aim of this study was to determine the efficacy and safety of rituximab in refractory PV. Methods: In an observational study extending from November 2014 to February 2016, 30 patients with refractory PV were treated with rituximab. Response ...
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The main treatment for pemphigus vulgaris are systemic corticosteroids and immunosuppressive agents, but due to adverse reactions and therapeutic failure, new drugs such as rituximab and mycophenolate mofetil have been used. In this case report are described two cases of severe pemphigus vulgaris refractory to various treatments, with resolution after use of rituximab and mycophenolate mofetil,...
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An otherwise healthy 53-year-old woman was admitted to our Dermatologic Clinic for evaluation of two erythematous plaques on the front and back of both her thighs, which had developed over the previous ten months (Figure 1A). These plaques showed vegetative or hypertrophic elements, and were occasionally pruritic. The rest of her skin and mucosal surfaces were normal, the patient being in good ...
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ژورنال
عنوان ژورنال: JAMA Dermatology
سال: 2015
ISSN: 2168-6068
DOI: 10.1001/jamadermatol.2014.3674